Denosumab for Osteoporosis
How Well It Works
In one large study denosumab was given to women every 6 months for 3 years. These women were compared to women who received an injection of liquid that did not contain the medicine (placebo). The women who were given denosumab had much less risk of breaking a bone, such as a spine or hipbone, than the women who were given the placebo.Reference 1
Androgen-deprivation therapy is known to decrease bone density. A study of men having androgen-deprivation therapy for prostate cancer compared a group of men who also received denosumab to a group who did not. The men who received denosumab had increased bone density and fewer spine fractures.Reference 2
| By: | Reference Healthwise Staff | Last Revised: November 6, 2012 |
| Medical Review: | Reference Kathleen Romito, MD - Family Medicine
Reference Carla J. Herman, MD, MPH - Geriatric Medicine |
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