Main content American Ginseng

    American Ginseng



    Uses

    Botanical names:
    Panax quinquefolius

    Parts Used & Where Grown

    Like its more familiar cousin Reference Asian ginseng (Panax ginseng), the root of American ginseng is used medicinally. The plant grows wild in shady forests of the northern and central United States, as well as in parts of Canada. It is cultivated in the United States, China, and France.

    What Are "Star" Ratings?

    Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

    For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

    3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.

    2 Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.

    1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

    This supplement has been used in connection with the following health conditions:

    Used for Why
    2 Stars
    Common Cold and Sore Throat
    400 mg per day of a freeze-dried extract
    In a double-blind study, supplementing with American ginseng significantly reduced the number of colds that people experienced over a four-month period.

    In a double-blind study, supplementation with Reference American ginseng significantly reduced by 27% the number of colds that people experienced over a four-month period, compared with a placebo.4 The amount used in this study was 400 mg per day of a freeze-dried extract.

    2 Stars
    Type 2 Diabetes
    3 grams with or following meals
    Supplementing with American ginseng may help improve blood sugar control.
    In a small preliminary trial, 3 grams of American ginseng was found to lower the rise in blood sugar following the consumption of a high-glucose drink by people with type 2 diabetes.5 The study found no difference in blood sugar–lowering effect if the herb was taken either 40 minutes before the drink or at the same time. A follow-up to this study found that increasing the amount of American ginseng to either 6 or 9 grams did not increase the effect on blood sugar following the high-glucose drink in people with type 2 diabetes.6 This study also found that American ginseng was equally effective in controlling the rise in blood sugar whether it was given together with the drink or up to two hours before.
    1 Star
    Infection
    Refer to label instructions
    American ginseng supports the immune system and protects against microbes.

    Traditional Use (May Not Be Supported by Scientific Studies)

    Many Native American tribes used American ginseng. Medicinal applications ranged from digestive disorders to sexual problems.1 The Chinese began to use American ginseng after it was imported during the 1700s.2 The traditional applications of American ginseng in China are significantly different from those for Panax ginseng (Asian ginseng).3

    How It Works

    Botanical names:
    Panax quinquefolius

    How It Works

    American ginseng contains ginsenosides, which are thought to fight fatigue and stress by supporting the adrenal glands and the use of oxygen by exercising muscles.7 The type and ratio of ginsenosides are somewhat different in American and Asian ginseng. The extent to which this affects their medicinal properties is unclear. A recent preliminary trial with healthy volunteers found no benefit in exercise performance after one week of taking American ginseng.8

    In a small pilot study, 3 grams of American ginseng was found to lower the rise in blood sugar following the consumption of a drink high in glucose by people with type 2 Reference diabetes.9 The study found no difference in blood sugar lowering effect if the herb was taken either 40 minutes before the drink or at the same time. A follow-up to this study found that increasing the amount of American ginseng to either 6 or 9 grams did not increase the effect on blood sugar following the high-glucose drink in people with type 2 diabetes.10 This study also found that American ginseng was equally effective in controlling the rise in blood sugar if it was given up to two hours before or together with the drink.

    How to Use It

    Standardized extracts of American ginseng, unlike Asian ginseng, are not available. However, dried root powder, 1–3 grams per day in capsule or tablet form, can be used.11 Some herbalists also recommend 3–5 ml of tincture three times per day.

    Interactions

    Botanical names:
    Panax quinquefolius

    Interactions with Supplements, Foods, & Other Compounds

    Conditions such as Reference insomnia or agitation are more likely to occur when Reference caffeine-containing foods and beverages are being consumed along with American ginseng.12

    Interactions with Medicines

    Certain medicines interact with this supplement.

    Types of interactions: Beneficial Adverse Check

    Replenish Depleted Nutrients

    • none

    Reduce Side Effects

    • none

    Support Medicine

    • none

    Reduces Effectiveness

    • none

    Potential Negative Interaction

    • Reference Warfarin

      In a study of healthy human volunteers, supplementing with American ginseng reduced warfarin's anticoagulant effect, apparently by stimulating the body to accelerate the metabolism of warfarin.13 People taking warfarin should not take American ginseng, unless supervised by a doctor.

    Explanation Required

    • none

    The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.

    Side Effects

    Botanical names:
    Panax quinquefolius

    Occasional cases of Reference insomnia or agitation have been reported with the use of American ginseng. These conditions are more likely, however, when Reference caffeine-containing foods and beverages are also being consumed.14

    Related Information

    American Ginseng

    References

    1. Duke J. Ginseng: A Concise Handbook. Algonac, MI: Reference Publications, 1989, 36.

    2. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine: Materia Medica. Seattle: Eastland Press, 1993, 358–9.

    3. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine: Materia Medica. Seattle: Eastland Press, 1993, 358–9.

    4. Predy GN, Goel V, Lovlin R, et al. Efficacy of an extract of North American ginseng containing poly-furanosyl-pyranosyl-saccharides for preventing upper respiratory tract infections: a randomized controlled trial. CMAJ 2005;173:1043–8.

    5. Vuksan V, Sivenpiper JL, Koo VY, et al. American ginseng (Panax quinquefolius L.) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009–13.

    6. Vuksan V, Sivenpiper JL, Koo VYY, et al. American ginseng (Panax quinquefolius L.) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009–13.

    7. Shibata S, Tanaka O, Shoji J, Saito H. Chemistry and pharmacology of Panax. Econ Med Plant Res 1:218–84.

    8. Morris AC, Jacobs I, McLellan TM, et al. No ergogenic effect on ginseng ingestion. Int J Sport Nutr 1996;6:263–71.

    9. Vuksan V, Sivenpiper JL, Koo VYY, et al. American ginseng (Panax quinquefolius L.) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009–13.

    10. Vuksan V, Sivenpiper JL, Koo VYY, et al. American ginseng (Panax quinquefolius L.) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009–13.

    11. Foster S. Herbs for Health. Loveland, CO: Interweave Press, 1996, 48–9.

    12. Yun TK, Choi Y. Preventive effect of ginseng intake against various human cancers: A case-control study on 1987 pairs. Cancer Epidem Biomarkers Prev 1995;4:401–8.

    13. Yuan CS, Wei G, Dey L, et al. Brief communication: American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled Trial. Ann Intern Med 2004;141:23–7.

    14. Yun TK, Choi Y. Preventive effect of ginseng intake against various human cancers: A case-control study on 1987 pairs. Cancer Epidem Biomarkers Prev 1995;4:401–8.


    Last Review: 11-07-2012

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    The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2013.



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