Main content Tricyclic Antidepressants for Premenstrual Syndrome (PMS)

    Tricyclic Antidepressants for Premenstrual Syndrome (PMS)



    What To Think About

    You may start to feel better in 1 to 3 weeks of taking antidepressant medicine. But it can take as many as 6 to 8 weeks to see more improvement. If you have questions or concerns about your medicines or if you do not notice any improvement by 3 weeks, talk to your doctor.

    Tricyclic antidepressants (TCAs) are taken orally every day throughout the menstrual cycle for premenstrual syndrome (PMS) symptoms. Typically, a low dose is given at first, and the dosage is increased slowly until the medicine takes effect. This helps minimize side effects.

    Taking medicine

    Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.

    There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Reference Taking Medicines as Prescribed.

    Advice for women

    If you are pregnant, breast-feeding, or planning to get pregnant, do not use any medicines unless your doctor tells you to. Some medicines can harm your baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all your doctors know that you are pregnant, breast-feeding, or planning to get pregnant.

    Checkups

    Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.

    Complete the new medication information form (PDF) Click here to view a form. (What is a Reference PDF Opens New Window document?) to help you understand this medication.



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