Corticosteroids (Glucocorticoids) for Cancer
Side Effects
Side effects are common with steroids and can include:
- Nausea, vomiting, stomach upset, or Reference ulcers Opens New Window. To reduce these side effects, take your pills with a full glass of fluid and a small snack.
- Fluid retention, causing swelling of the hands and feet.
- Increased appetite.
- Increased risk of infection.
- Preexisting Reference diabetes Opens New Window getting worse.
- Menstrual period changes.
- Changes in behavior, such as symptoms of paranoia or Reference psychosis Opens New Window.
- Muscle wasting. You may notice that it is difficult to climb stairs or rise from sitting to standing without assistance.
Some problems may occur with long-term use. These include:
- Reference Osteoporosis Opens New Window.
- Reference Cataract Opens New Window formation.
- Reference High blood pressure Opens New Window.
- Development of diabetes.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
| By: | Reference Healthwise Staff | Last Revised: October 28, 2011 |
| Medical Review: | Reference E. Gregory Thompson, MD - Internal Medicine
Reference Michael Seth Rabin, MD - Medical Oncology |
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This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Reference Terms of Use. Reference How this information was developed to help you make better health decisions.

