Alosetron for Irritable Bowel Syndrome
What To Think About
Alosetron can cause a very serious side effect called Reference ischemic colitis Opens New Window. This happens when blood flow to the large intestine is reduced. Symptoms of ischemic colitis include severe constipation, abdominal pain, rectal bleeding, and bloody diarrhea. If you have any of these symptoms, stop taking the medicine and call your doctor right away.
If you have ischemic colitis, you may need surgery to fix it. Some people who got ischemic colitis while taking alosetron died. Because of this dangerous side effect, alosetron is only used in women who have severe IBS with diarrhea and who have not had success with any other treatment for IBS. People taking alosetron must sign a consent form before starting to take the medicine, and only certain doctors can prescribe this medicine.
Taking medicine
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Reference Taking Medicines as Prescribed.
Advice for women
If you are pregnant, breast-feeding, or trying to get pregnant, do not use any medicines unless your doctor tells you to. Some medicines can harm your baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all your doctors know that you are pregnant, breast-feeding, or planning to get pregnant.
Checkups
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF) 
(What is a Reference PDF Opens New Window document?) to help you understand this medication.
| By: | Reference Healthwise Staff | Last Revised: April 26, 2012 |
| Medical Review: | Reference E. Gregory Thompson, MD - Internal Medicine
Reference Arvydas D. Vanagunas, MD - Gastroenterology |
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This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Reference Terms of Use. Reference How this information was developed to help you make better health decisions.
