Main content Gonadotropin-Releasing Hormone Agonist (GnRH-a) Therapy for Endometriosis

    Gonadotropin-Releasing Hormone Agonist (GnRH-a) Therapy for Endometriosis



    Examples

    Gonadotropin-releasing hormone agonists

    Brand NameGeneric NameChemical Name
    Zoladex goserelin
    Lupron Depot leuprolide
    Synarel nafarelin

    How these medicines are taken

    • Leuprolide is injected into muscle (intramuscularly) once a month. It is also available in a dose that lasts for 3 months.
    • Nafarelin is sprayed into the nose (intranasally) twice a day.
    • Goserelin 3.6 mg pellet is injected under the skin of the abdomen (subcutaneously) once every 28 days. Your body gradually absorbs the pellet.


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