Total Serum Protein
A total serum protein test measures the total amount of Reference protein Opens New Window in the blood. It also measures the amounts of two major groups of proteins in the blood: albumin and globulin.
- Albumin is made mainly in the liver. It helps keep the blood from leaking out of blood vessels. Albumin also helps carry some medicines and other substances through the blood and is important for tissue growth and healing.
- Globulin is made up of different proteins called alpha, beta, and gamma types. Some globulins are made by the liver, while others are made by the Reference immune system Opens New Window. Certain globulins bind with Reference hemoglobin Opens New Window. Other globulins transport metals, such as iron, in the blood and help fight infection. Serum globulin can be separated into several subgroups by serum protein electrophoresis. For more information, see the topic Reference Serum Protein Electrophoresis.
A test for total serum protein reports separate values for total protein, albumin, and globulin. Some types of globulin (such as alpha-1 globulin) also may be measured.
|By:||Reference Healthwise Staff||Last Revised: Reference November 4, 2011|
|Medical Review:||Reference E. Gregory Thompson, MD - Internal Medicine
Reference Jerome B. Simon, MD, FRCPC, FACP - Gastroenterology