Test Menu and Information

Important Note:

Testing must be ordered by a physician. Results can only be reported to the ordering physician or the referring laboratory. Patients desiring testing and/or test results are advised to consult their physician. We require specimen tubes to be labeled with the patient's name (first and last) and collection date. Unlabeled tubes will not be accepted for testing.  We also cannot test grossly hemolyzed samples.


Clinical Laboratory Scientists

Judy Beatty
Judy Beatty
Bernadett Domingo
Bernadett Domingo
Helen Canevari
Helen Canevari
Beverly Gaylord
Beverly Gaylord
Michiko Matsuura
Michiko Matsuura
Kathleen Messing
Kathleen Messing
Cindy Press
Cindy Press
Raymund Ramirez
Raymund Ramirez
Joe Wagoner
Not Shown

Click test name for information

Effective: February, 2009


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IgG (Dye Test)

Reference range:

negative < 1:16; positive > 1:16

Specimen:

serum, CSF

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86777

Fee:

$114

Method Reference:

Sabin AB, Feldman HA. Dyes as microchemical indicators of a new immunity phenomenon affecting a protozoan parasite (Toxoplasma). Science 108:660-663, 1948.

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IgM ELISA
(for patients 6 months of age or older)

Reference range:

negative 0.0-1.4, equivocal 1.7-1.9, positive > 2.0 (serum) negative 0.0 - 0.3, positive > 0.4 (CSF)

Specimen:

serum, CSF

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86778

Fee:

$121

Method Reference:

Naot Y, Remington J. An enzyme-linked immunosorbent assay for detection of IgM antibodies to Toxoplasma gondii : use for diagnosis of acute acquired toxoplasmosis. J Infect Dis 142:757-766, 1980

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IgM ISAGA
(for patients less than 6 months of age)

Reference range:

reported as positive or negative

Specimen:

serum

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86778

Fee:

$121

Method Reference:

Desmonts G, Naot Y, Remington JS. Immunoglobulin M immunosorbent agglutination assay for diagnosis of acute congenital and acquired toxoplasma infections. J Clin Microbiol 14:486-491, 1981

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IgA ELISA

Reference range:

reported as positive or negative

Specimen:

serum

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86777-59

Fee:

$126

Method Reference:

Stepick-Biek P, Thulliez P, Araujo F, Remington JS. IgA antibodies for diagnosis of acute congenital and acquired toxoplasmosis. J Infect Dis 162:270-273, 1990

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IgE ELISA
(offered as component of Toxo Panels only)

Reference range:

negative

Specimen:

serum

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86777-59

Fee:

$126

Method Reference:

Wong S, Hadju M, Ramirez R, Thulliez P, McLeod R, Remington JS. Role of specific immunoglobulin E in diagnosis of acute toxoplasma infection and toxoplasmosis. J Clin Microbiol 31:2952-2959, 1993

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AC/HS (Differential Agglutination)

Reference range:

(refer to table)

Specimen:

serum

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86406 (2 units)

Fee:

$130

Method Reference:

Danneman B, Vaughn W, Thulliez P, Remington JS. Differential agglutination test for diagnosis of recently acquired infection with Toxoplasma gondii. J Clin Microbiol 28:1928-1933, 1990

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Avidity (IgG (Dye test) and IgM ELISA will also be performed)

Reference range:

high avidity excludes infection within the previous 4 months

Specimen:

serum

Volume:

0.5 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

86777-59

Fee:

$351 (Includes fee for IgG (Dye test) and IgM ELISA)

Method Reference:

Pelloux, H. et al. Determination of anti-Toxoplasma gondii immunoglobulin G avidity: adaption to the Vidas system (bioMérieux). Diagn Microbiol Infect Dis 32: 69-73, 1998

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PCR

Reference range:

reported as positive or negative

Specimen:

(refer to PCR Specimen Requirements table)

Volume:

(refer to PCR Specimen Requirements table)

Transport temperature:

(refer to PCR Specimen Requirements table)

CPT code:

83890, 83896 (2 units), 83898 (2 units)

Fee:

$398 (refer to Fee Schedule)

Method References:

Grover C, Thulliez P, Remington J, Boothroyd J. Rapid prenatal diagnosis of congenital Toxoplasma infection by using polymerase chain reaction and amniotic fluid. J Clin Microbiol 28:2297-2301, 1990.

Parmley S, Goebel F, Remington JS. Detection of Toxoplasma gondii in cerebro-spinal fluid from AIDS patients by polymerase chain reaction. J Clin Microbiol 30:3000-3002, 1992

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Isolation

Reference range:

reported as positive or negative

Specimen:

whole blood, amniotic fluid, placenta and other tissues

NOTE: Specimens must not be frozen or placed in formalin or other fixative. Inoculations are recommended within 48 hours of specimen collection date. Results available in six weeks.

Volume:

3 ml (fluids); 1 g (solid tissues)

Transport temperature:

2 – 8° C.

CPT code:

87003

Fee:

$429

Method Reference:

Remington J.S., McLeod R., Thulliez P., Desmonts G. Toxoplasmosis.

In Remington J.S., Wilson C.B., Baker C.J. and Klein, J.O. (eds.) Infectious Diseases of the Fetus and Newborn Infant, Sixth Edition. Philadelphia: Elsevier Saunders Company, 2006, pp 1009-1010.

PANELS

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IgG/IgM Toxo Panel:

  • IgG (Dye Test), IgM ELISA or IgM ISAGA

Specimen:

serum

Volume:

0.5 to 1.0 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

Refer to individual tests above

Fee:

$221

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Toxoplasma Pregnancy Panel (16 weeks gestation or earlier):

  • IgG (Dye Test), IgM ELISA, Avidity

Specimen:

serum

Volume:

0.5 to 1.0 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

Refer to individual tests above

Fee:

$351

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Toxoplasma Pregnancy Panel (more than 16 weeks gestation):

  • IgG (Dye Test), IgM ELISA, AC/HS

Specimen:

serum

Volume:

0.5 to 1.0 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

Refer to individual tests above

Fee:

$351

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Toxoplasma Infant Panel: (less than 6 months of age)

  • IgG (Dye Test), IgM ISAGA, IgA ELISA

Specimen:

serum

Volume:

1.0 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

Refer to individual tests above

Fee:

$338

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Toxoplasma Panel: (6 months of age or older)

  • IgG (Dye Test), IgM ELISA, IgA ELISA, IgE ELISA, AC/HS

Specimen:

serum

Volume:

2.0 ml

Transport temperature:

2 – 8° C. (preferred); ambient or frozen (acceptable)

CPT code:

Refer to individual tests above

Fee:

$528