Bupropion (Zyban) for Quitting Smoking

Like other treatments, bupropion works best when it is part of a program that includes setting a quit date; having a plan for dealing with things that make you reach for a cigarette (smoking triggers); and getting support from a doctor, counselor, or support group.

Using bupropion along with nicotine replacement therapy (such as nicotine patches, gum, or inhaler) may work better than either therapy alone. Talk to your doctor before combining bupropion with nicotine replacement therapy.

Bupropion should not be used during pregnancy unless you and your doctor decide the benefits outweigh the risks and you are unable to quit smoking without using medicine. Talk with your doctor about whether you can use this medicine during pregnancy. Women should not breast-feed while taking this medicine.

Complete the new medication information form (PDF) (What is a Reference PDF Opens New Window document?) to help you understand this medication.

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