What Are "Star" Ratings?
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2 Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
This supplement has been used in connection with the following health conditions:
Refer to label instructions
Used under a doctor’s supervision, adrenal cortext extract may relieve nausea and vomiting during early pregnancy.
In a preliminary study done in the 1930s, eight women suffering from nausea and vomiting during the first trimester (13 weeks) of Reference pregnancy received large amounts of oral Reference adrenal cortex extract. In most cases, vomiting stopped after three to four days.1 In a follow-up study, women with nausea and vomiting of pregnancy received adrenal cortex extract, usually by injection at first, followed by oral administration. More than 85% of the women were completely relieved of the problem or showed definite improvement.2 Since no safety data exist for use during pregnancy, adrenal extract should not be used in these situations unless supervised by a doctor.
How It Works
How to Use It
The amount of adrenal extract taken will depend upon the quality and potency of the product. Follow the recommendations given on the product label or those given by your healthcare provider.
Where to Find It
Adrenal extracts are available in capsules or tablets. Adrenal extracts prepared for injection were commonly used at one time, but currently are unavailable.
As adrenal extract is not an essential nutrient, no nutritional deficiency state exists. However, some people have suboptimal adrenal function or frank adrenal insufficiency. The diagnosis of adrenal problems should be made by a physician.
Interactions with Supplements, Foods, & Other Compounds
Interactions with Medicines
Stomach irritation and/or nausea is a common side effect, especially with higher potency products. Other possible side effects include a general stimulatory effect that may manifest as Reference anxiety, irritability, and/or Reference insomnia. Since no safety data exist for use during Reference pregnancy or breast-feeding, adrenal extract should not be used in these situations unless supervised by a doctor.
Consumption of excessive amounts may produce signs and symptoms of corticosteroid excess similar to those experienced with the drug prednisone. However, serious side effects are not likely to result from taking a large amount of an adrenal extract for a short period of time or from excessive intake on a single occasion, but rather from long-term use of high amounts. With prednisone (a synthetic cortisone-like drug) at lower doses (less than 10 mg per day), the most notable side effects are usually increased appetite, weight gain, retention of salt and water, and increased susceptibility to Reference infection.
1. Kemp WN. Hyperemesis gravidarum treated as a temporary adrenal cortex deficiency. Can Med Assoc J 1933;28:389–91.
2. Kemp WN. The vomiting of pregnancy treated as a temporary relative insufficiency of maternal corticoadrenal function. Med Rec 1934;140:239–41.
Last Review: 11-07-2012
Copyright © 2012 Aisle7. All rights reserved. Aisle7.com
The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2013.