Reference Propolis is the resinous substance collected by bees from the leaf buds and bark of trees, especially poplar and conifer trees. Propolis extracts may be helpful in preventing and shortening the duration of the common cold. A preliminary clinical trial reported propolis extract (daily dose not given) reduced upper respiratory infections in children.¹ In one small, double-blind trial of propolis for the common cold, the group taking propolis extract (amount unstated) became free of symptoms more quickly than the placebo group.² Most manufacturers recommend 500 mg of oral propolis products once or twice daily.

In a preliminary study of women with infertility and mild endometriosis, supplementation with Reference propolis (500 mg twice a day for six months) was associated with a pregnancy rate of 60%, compared with a rate of 20% in the placebo group (a statistically significant difference).³ Whether propolis would be beneficial for infertile women who do not have endometriosis is not known.

A test tube study found that Reference flavonoids present in Reference propolis are responsible for the supplement’s antiviral action.⁴ A controlled study found that an ointment containing propolis, used four times daily, was almost twice as effective as topical antiviral medication or a placebo ointment.⁵

Reference Propolis is a resinous substance collected by bees from the leaf buds and bark of trees, especially poplar and conifer trees. The antimicrobial properties of propolis may help protect against parasitic Reference infections in the gastrointestinal tract. One preliminary trial of propolis extract for children and adults with giardiasis showed a 52% rate of successful parasite elimination in children and a 60% elimination rate in adults (amount not stated).⁶ These results are not as impressive as those achieved with conventional drugs for giardiasis, though, so propolis should not be used as the sole therapy for parasites without first consulting a physician about available medical treatment.

Reference Propolis is the resinous substance collected by bees from the leaf buds and bark of trees, especially poplar and conifer trees. Anti-inflammatory effects from topical application of propolis extract have been noted in one animal study,⁷and a preliminary controlled trial found that patients with RA treated with topical propolis extract (amount and duration not noted) had greater improvements in symptoms compared to placebo.⁸

In a preliminary study, topical application of an alcohol extract of Brazilian Reference propolis resolved candidiasis in 12 of 12 people who were experiencing oral candidiasis associated with the use of dentures. The extract, which was prepared by mixing 2 grams of dried propolis in 25 ml of an 80:20 alcohol:water solution, was applied to the lesions four times a day for seven days.⁹

Application of an ointment containing Reference propolis, the resin collected by bees from trees, has been shown to relieve genital herpes more effectively than topical acyclovir.¹⁰ It is likely that this treatment might also benefit people with cold sores, although this has not been tested. Propolis ointment should be applied four times per day.