Lupus and Antiphospholipid Antibody Syndrome
About 1 out of 3 people with Reference lupus Opens New Window produce an Reference antibody Opens New Window that attacks certain blood-clotting factors, which can cause the blood to clot easily.Reference 1 A person who has this antibody and has had blood clots is said to have antiphospholipid antibody syndrome. This can lead to mild or severe blood-clotting complications, including:
- Reference Stroke Opens New Window, Reference transient ischemic attack (TIA) Opens New Window, or Reference heart attack Opens New Window.
- Reference Deep vein thrombosis Opens New Window or Reference pulmonary embolism Opens New Window.
- Reference Multi-infarct dementia Opens New Window.
- Reference Gangrene Opens New Window of fingers or toes.
- Reference Kidney Opens New Window disease.
- Reference Preeclampsia Opens New Window, premature birth, and Reference miscarriage or stillbirth Opens New Window, apparently caused by blood circulation problems in the Reference placenta Opens New Window.
A blood test can detect antiphospholipid antibodies. When diagnosed, the condition is usually treated with Reference anticoagulants Opens New Window. Pregnant women with antiphospholipid antibody syndrome need to be closely monitored.
|By:||Reference Healthwise Staff||Last Revised: Reference May 10, 2012|
|Medical Review:||Reference Anne C. Poinier, MD - Internal Medicine
Reference Nancy Ann Shadick, MD, MPH - Internal Medicine, Rheumatology