Decongestants and Nasal Sprays

Decongestants or nasal sprays may help relieve a stuffy nose.

Decongestants shrink swollen tissues in the space behind the eardrum (Reference middle ear Opens New Window Reference Opens New Window). This may relieve pressure and pain. They can be taken by mouth (oral) or in nose drops or sprays. Oral decongestants are probably more effective and provide longer relief than drops or sprays, but they cause more side effects.

Sprays and drops provide rapid but temporary relief. Sprays and drops are less likely to interact with other medicines, which can be a problem with oral decongestants.

Decongestant precautions

• Look for a single-ingredient decongestant that contains pseudoephedrine or phenylephrine.
• Be careful with these medicines. They may not be safe for young children or for people who have certain health problems, so check the label first. If you do use these medicines, always follow the directions about how much to use based on age and weight. For your baby, you can use a suction bulb to gently remove mucus from your baby's nose.
• Do not use medicated nasal sprays or drops more often than directed and not longer than 3 days. Continued use will cause your mucous membranes to swell more than before using the spray (rebound effect).
• Drink extra fluids when you are taking cold medicines.
• If you are not certain about which decongestant to use, ask your Reference pharmacist Opens New Window or doctor for help.
  • Decongestants can cause problems for people who have other health problems such as Reference heart disease Opens New Window, Reference high blood pressure Opens New Window, Reference prostate Opens New Window problems, Reference glaucoma Opens New Window, Reference diabetes Opens New Window, or Reference hyperthyroidism Opens New Window.
  • Decongestants also may interact with other medicines such as some antidepressants and high blood pressure medicines.

For more information about medicine safety, see the topics Reference Over-the-Counter Medicine Precautions and Reference Quick Tips: Giving Over-the-Counter Medicines to Children.

You also can make a Reference saline solution nasal spray Opens New Window or use a Reference humidifier Opens New Window to help thick or dried mucus to drain. These will not cause Reference rebound Opens New Window symptoms.

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