What To Think About
- If the ALP level is high, other tests may be done to determine whether a liver or bone problem is present.
- If liver disease is suspected, more blood tests, an Reference ultrasound Opens New Window, or a Reference CT scan Opens New Window are generally recommended to find the problem.
- Other tests to check liver function, such as alanine aminotransferase, aspartate aminotransferase, and bilirubin, are often done at the same time as an alkaline phosphatase (ALP) test. For more information, see the topics Reference Alanine Aminotransferase (ALT), Reference Aspartate Aminotransferase (AST), and Reference Bilirubin.
- Gamma glutamyl transferase (GGT), or gamma glutamyl transpeptidase, may be measured in the blood to check the difference between bone ALP and liver ALP. High levels of GGT are present when the liver is damaged but not present with bone disease. A high level of GGT may be caused by alcohol use or may mean that blocked bile ducts are causing inflammation. The level of GGT may be high with the use of certain medicines, such as phenytoin and phenobarbital. In some medical centers, a test that measures a substance called 5-nucleotidase is done instead of the GGT test because it is better at finding liver disease.
|By:||Reference Healthwise Staff||Last Revised: Reference June 20, 2012|
|Medical Review:||Reference E. Gregory Thompson, MD - Internal Medicine
Reference Alan C. Dalkin, MD - Endocrinology