Indomethacin for Slowing Preterm Labor

• Indomethacin is used with caution, particularly for pregnant women with heart disease, asthma, a history of intestinal bleeding or ulcers, kidney disease, problems with blood clotting, or a decreased amount of amniotic fluid (oligohydramnios). It is also not used during the last 2 months of pregnancy because of possible effects on fetal heart development.
• When indomethacin is used for more than 3 to 7 days, fetal monitoring with an Reference echocardiogram Opens New Window and regular Reference ultrasound Opens New Window tests on the mother are used to check the amount of amniotic fluid.

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