Cone Biopsy (Conization) for Abnormal Cervical Cell Changes

Cone biopsy (conization) can be done using a carbon dioxide laser or loop electrosurgical excision procedure (LEEP). One possible disadvantage of these methods is that the abnormal tissue at the margin with the normal tissue can be changed by the heat from the laser beam or the wire loop. This may make the laboratory study of the biopsied tissue more difficult.

If you have a cone biopsy, you need regular follow-up Pap tests and colposcopic examinations. A Pap test should be repeated every 4 to 6 months or as recommended by your doctor. After several Pap test results are normal, you and your doctor can decide how often to schedule future Pap tests.

The healing and scarring process after a cone biopsy may make it hard to identify abnormal tissue in the future.

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