HealthWise KnowledgeBase
Total Serum Protein
Results
A total serum protein test is a blood test that measures the amounts of total Reference protein Opens New Window, albumin, and globulin in the blood. Results are usually available within 12 hours.
Normal
The normal values listed here—called a reference range—are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what’s normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.
|
Total protein: |
6.4–8.3 Reference grams per deciliter (g/dL) Opens New Window or 64–83 Reference grams per liter (g/L) Opens New Window |
|---|---|
|
Albumin: |
3.5–5.0 g/dL or 35–50 g/L |
|
Alpha-1 globulin: |
0.1–0.3 g/dL or 1–3 g/L |
|
Alpha-2 globulin: |
0.6–1.0 g/dL or 6–10 g/L |
|
Beta globulin: |
0.7–1.1 g/dL or 7–11 g/L |
High values
High albumin levels may be caused by:
High globulin levels may be caused by:
- Diseases of the blood, such as multiple myeloma, Reference Hodgkin's lymphoma Opens New Window, Reference leukemia Opens New Window, macroglobulinemia, or Reference hemolytic anemia Opens New Window.
- An Reference autoimmune disease Opens New Window, such as Reference rheumatoid arthritis Opens New Window, Reference lupus Opens New Window, autoimmune Reference hepatitis Opens New Window, or Reference sarcoidosis Opens New Window.
- Kidney disease.
- Liver disease.
- Reference Tuberculosis Opens New Window.
Low values
Low albumin levels may be caused by:
- A poor diet (malnutrition).
- Kidney disease.
- Liver disease.
- An autoimmune disease, such as lupus or rheumatoid arthritis.
- Gastrointestinal malabsorption syndromes, such as Reference sprue Opens New Window or Reference Crohn's disease Opens New Window.
- Hodgkin's lymphoma.
- Uncontrolled Reference diabetes Opens New Window.
- Reference Hyperthyroidism Opens New Window.
- Reference Heart failure Opens New Window.
This information does not replace the advice of a doctor. Healthwise, Incorporated disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Reference Terms of Use. Reference How this information was developed to help you make better health decisions.

