HealthWise KnowledgeBase
Methotrexate
How It Works
Methotrexate is similar to the vitamin called folic acid. It works by competing with folic acid in cells. This blocks the way the cell is able to make genetic material, and the cell dies.
Methotrexate may be given as a pill or as a shot in the vein (intravenously, or IV) or in the muscle (intramuscularly, or IM).
| By: | Reference Healthwise Staff | Last Revised: June 28, 2011 |
| Medical Review: | Reference Sarah Marshall, MD - Family Medicine
Reference Douglas A. Stewart, MD - Medical Oncology |
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