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    Combination Drug Therapy for Peptic Ulcer Disease

    Combination Drug Therapy for Peptic Ulcer Disease



    Examples

    Combination drug therapy regimens

    Combination drug therapy regimens commonly used to treat an H. pylori infection include the following options:

    • A proton pump inhibitor (PPI) plus clarithromycin plus amoxicillin or metronidazole
    • A proton pump inhibitor plus a bismuth compound plus metronidazole plus tetracycline

    Antibiotics

    Some examples of antibiotics used to treat H. pylori are:

    Brand NameGeneric NameChemical Name
      amoxicillin
    Biaxin clarithromycin
    Flagyl metronidazole
      tetracycline

    Prepackaged drug combinations

    Some of the recommended drug combinations are packaged together for convenience.

    Brand NameGeneric NameChemical Name
    Pylera bismuth subcitrate potassium and metronidazole and tetracycline
    Helidac bismuth subsalicylate and metronidazole and tetracycline
    Prevpac lansoprazole (a PPI) and amoxicillin and clarithromycin
      omeprazole (a PPI) and amoxicillin and clarithromycin


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