Psoralen and UVA Light Therapy (PUVA) for Psoriasis

PUVA is used to treat moderate to severe psoriasis (covering more than 20% of the skin).

PUVA is used to treat psoriasis that has not responded to creams, ointments, or tar products used with UV exposure (phototherapy). It should be used in the lowest doses possible. Higher doses and more exposure increase the risk of skin cancer.

Psoralens should not be used by:

• Children under age 12, because the UV light therapy may cause cataracts.
• People who have diseases that make their skin more sensitive to sunlight (such as Reference lupus Opens New Window).
• Fertile men and women who do not use birth control. There is a small risk of birth defects.
• Pregnant women, because of possible effects on a Reference fetus Opens New Window.

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