Methotrexate for Psoriasis
Common temporary side effects include:
- Nausea, fatigue, loss of appetite.
- Trouble sleeping.
- Low blood counts.
Less common temporary side effects include:
- Sunburn if you are exposed to large doses of sunlight or Reference ultraviolet (UV) light Opens New Window either before or after taking the drug.
- Vomiting, diarrhea, and occasional blood in the stools.
- Mouth sores.
- Easy bruising and bleeding.
- Skin rash or sores.
- Chills and fever.
- Birth defects (if taken by a woman who is pregnant or who becomes pregnant while taking the medicine).
Long-term side effects include liver damage. If it is not severe, the damage reverses after you stop taking methotrexate. The risk of liver damage is higher if you drink a lot of alcohol, have kidney or liver problems or diabetes, or are overweight.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
|By:||Reference Healthwise Staff||Last Revised: January 9, 2012|
|Medical Review:||Reference Adam Husney, MD - Family Medicine
Reference Amy McMichael, MD - Dermatology